Membrance bearer protein include P-glycoprotein ( P-gp) multidrug resistance relative protein ( MRP), lung resistance protein ( LRP), breast cancer resistance protein ( BCRP), and so on. They belonged to ABC transport protein superfamily except LRP. 膜转运蛋白包括P-糖蛋白(P-glycoprotein,P-gp)、多药耐药相关蛋白(MRP)、肺耐药蛋白(LRP)和乳癌耐药蛋白(BCRP)等几类,除LRP外均属于ABC转运蛋白超家族成员;
ABC ( ATP Binding Cassette) membrance bearer protein is involved in MDR. 白血病细胞经典的耐药机制涉及到ABC(ATPBindingCassette,ATP结合盒)型膜载体蛋白家族。